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Enzyme Polymorphism

24. October 2011 by Richard S. Lord, PhD 2 Comments

Molecule

Understanding molecular medicine requires understanding how the molecules of the human body interact, and how their activities can be changed by nutrient supplementation.

 

 

 Can't see the video above? Click here to open on YouTube.

 

We Have Unique Nutritional Needs

  • Gene-618a/b → Protein618a/b
  • The pyruvate dehydrogenase complex
    1. Glucose → Pyruvate (→) Acetyl-CoA → CO2 + H2O
    2. Thiamin responsive pyruvic and lactic acidemia
      • 100+-fold differences amongst individual
    3. PDC structure
    4. Thiamin pyrophosphate binding site
      • Effects of active site amino acid changes
  • Generalize to all enzymes – endless permutations
    1. Where are your metabolic weaknesses?
      • Testing can reveal them

    ~ Dr. Richard S. Lord

    Resources:
    Laboratory Evaluations for Integrative and Functional Medicine

Comments (2) -

Angela Walker
Angela Walker United Kingdom
11/3/2011 8:56:55 AM #

I just love this series of video clips; they are brilliant, please can we have more!! And please can you create an app that take all of Dr Lords biochemical knowledge and plugs it into my brain???

Ange

Reply

Barb
Barb
4/2/2012 4:21:10 AM #

Well done. Thats just the sort of stimulus I wanted for it.

Reply

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